What is plasmapheresis?

To define plasmapheresis in a simple way, we could say that it is a blood filtering treatment. However, plasmapheresis is a term used to refer to a wide range of procedures in which an extracorporeal separation of blood components results in a filtered plasma product.

Plasmapheresis is a process in which the liquid in the blood, or plasma, is separated from the cells. Plasma can contain antibodies that attack the immune system. In the process, only healthy components of the blood which are smaller can go through device membranes/filters while the immune complexes that actually cause the inflammation are being removed from the blood stream and replaced with good plasma, or plasma substitute. This is also known as plasma exchange.

Plasmapheresis procedure or extracorporeal detoxification method is one of the most effective modern methods of detoxification. It is most commonly applied in drug detoxification and the reduction of abstinence syndrome. The essence of the method lies in the fact that the patient’s blood is passed through a special membrane of the plasmapheresis machine that works as a filter for poisonous toxins, drugs, and damaged cells. The effectiveness of this method is conditioned by its detoxifying, immunomodulating and anti-inflammatory properties. Plasmapheresis is widely used at the initial stage of a complex therapy. It enhances the efficiency of a continued treatment and regenerates the patient’s organism. It is prescribed only after a consultation with a doctor.

How is it done?

The procedure is carried out in a medical facility under the strict supervision of experts. The liquid part of the blood with toxins is separated and plasma re-enters the body free of harmful substances. After plasmapheresis, the blood is less sticky which also contributes to the cleansing of tissue and internal organs.

The filtering of the plasma from whole blood can be accomplished via centrifugation or the use of semipermeable membranes – Plasmapheresis device. Centrifugation takes advantage of the different specific gravities inherent in various blood products, such as red blood cells (RBCs), white blood cells (WBCs), platelets, and plasma. Membrane plasma separation uses the differences in particle size to filter plasma from the cellular components of blood.

In therapeutic plasma exchange, using an automated centrifuge, the filtered plasma is discarded and red blood cells, along with replacement colloid such as donor plasma or albumin, is returned to the patient. In membrane plasma filtration, secondary membrane plasma fractionation can selectively remove undesired macromolecules, which then allows return of the processed plasma to the patient instead of donor plasma or albumin. Examples of secondary membrane plasma fractionation include cascade filtration, thermofiltration, cryofiltration, and low-density lipoprotein apheresis.

How is it done?

The procedure is carried out in a medical facility under the strict supervision of experts. The liquid part of the blood with toxins is separated and plasma re-enters the body free of harmful substances. After plasmapheresis, the blood is less sticky which also contributes to the cleansing of tissue and internal organs.

The filtering of the plasma from whole blood can be accomplished via centrifugation or the use of semipermeable membranes – Plasmapheresis device. Centrifugation takes advantage of the different specific gravities inherent in various blood products, such as red blood cells (RBCs), white blood cells (WBCs), platelets, and plasma. Membrane plasma separation uses the differences in particle size to filter plasma from the cellular components of blood.

In therapeutic plasma exchange, using an automated centrifuge, the filtered plasma is discarded and red blood cells, along with replacement colloid such as donor plasma or albumin, is returned to the patient. In membrane plasma filtration, secondary membrane plasma fractionation can selectively remove undesired macromolecules, which then allows return of the processed plasma to the patient instead of donor plasma or albumin. Examples of secondary membrane plasma fractionation include cascade filtration, thermofiltration, cryofiltration, and low-density lipoprotein apheresis.

What is it used for?

Plasmapheresis is currently used as a therapeutic modality in a wide array of conditions. Generally, it is used when a substance in the plasma, such as immunoglobulin, is acutely toxic and can be efficiently removed. Myriad conditions that fall under this category (including neurologic, hematologic, metabolic, dermatologic, rheumatologic, and renal diseases as well as intoxications) can be treated with plasmapheresis.

In the drug detoxification treatment process, plasmapheresis does not only reduce the symptoms of withdrawal syndrome, but kick-starts the metabolism and immunity. The experience in treating patients with substance abuse shows a high efficiency of the complex course of the therapeutic plasmapheresis. In all cases, up to the end of the course there was a gradual elimination of withdrawal syndrome symptoms where somatic-vegetative disorders were normalized while normal sleep, appetite and psycho-emotional status were normalized.

Plasmapheresis is also used in other areas of medicine as a very powerful tool against allergies and autoimmune reactions. This process easies the operation of the internal organs such as liver and kidney.

What is it used for?

Plasmapheresis is currently used as a therapeutic modality in a wide array of conditions. Generally, it is used when a substance in the plasma, such as immunoglobulin, is acutely toxic and can be efficiently removed. Myriad conditions that fall under this category (including neurologic, hematologic, metabolic, dermatologic, rheumatologic, and renal diseases as well as intoxications) can be treated with plasmapheresis.

In the drug detoxification treatment process, plasmapheresis does not only reduce the symptoms of withdrawal syndrome, but kick-starts the metabolism and immunity. The experience in treating patients with substance abuse shows a high efficiency of the complex course of the therapeutic plasmapheresis. In all cases, up to the end of the course there was a gradual elimination of withdrawal syndrome symptoms where somatic-vegetative disorders were normalized while normal sleep, appetite and psycho-emotional status were normalized.

Plasmapheresis is also used in other areas of medicine as a very powerful tool against allergies and autoimmune reactions. This process easies the operation of the internal organs such as liver and kidney.

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What Results Can You Expect?

What Results Can You Expect?

PLASMAPHERESIS-results
  • Athletes use this method to recover after an intensive course of steroids;
  • Plasmapheresis significantly reduces the risk of delirium and other psychotic disorders;
  • It reduces blood viscosity and the risk of thrombi whilst preventing thrombosis;
  • It improves the blood flow to organs and tissues and it corrects the functions of the affected organs;
  • It reduces the size of atheroma plaques, restores blood flow in the blood vessels, and eliminates the risk of amputation of the lower limbs;
  • It eliminates the waste from the blood produced by viruses and bacteria and it improves the retrogression of the disease;
  • It purifies the blood of antibodies and immune circulating complexes;
  • It reduces the intensity of clinical symptoms and exacerbation signs;
  • It enhances sensitivity to medication and significantly decreases the doses of medical preparations (patients are helped by much smaller doses of medication);
  • It purifies the blood and tissues of the accumulated toxic and harmful substances;
  • It helps with the rejuvenation of the entire body.
  • Athletes use this method to recover after an intensive course of steroids;
  • Plasmapheresis significantly reduces the risk of delirium and other psychotic disorders;
  • It reduces blood viscosity and the risk of thrombi whilst preventing thrombosis;
  • It improves the blood flow to organs and tissues and it corrects the functions of the affected organs;
  • It reduces the size of atheroma plaques, restores blood flow in the blood vessels, and eliminates the risk of amputation of the lower limbs;
  • It eliminates the waste from the blood produced by viruses and bacteria and it improves the retrogression of the disease;
  • It purifies the blood of antibodies and immune circulating complexes;
  • It reduces the intensity of clinical symptoms and exacerbation signs;
  • It enhances sensitivity to medication and significantly decreases the doses of medical preparations (patients are helped by much smaller doses of medication);
  • It purifies the blood and tissues of the accumulated toxic and harmful substances;
  • It helps with the rejuvenation of the entire body.

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